Manchester United v Lyon Betting Tips [17 April 2025]

Manchester United will look to keep their Europa League hopes alive when they host Lyon for their quarter-final return leg match. From the first leg, this tie is balanced at 2-2, and the winner on aggregate will advance to face Rangers or Athletic Bilbao. Read on for our prediction.

Manchester United are having a torrid season domestically, and all their hopes of silverware this season are in this competition. The Europa League is also their only pathway to Europe next season.

It is, therefore, unsurprising to see the effort put in here. The Red Devils are coming off a 4-1 loss to Newcastle United but are unbeaten at home in 10 Europa League matches.

Lyon failed to make the most of their home game in this tie, only grabbing a late equalizer to avoid defeat. They have everything to play for away from home and have to contend with Manchester United’s fine run at home in this competition.

The French side geared up for this match with a 3-1 away win at Auxerre. That marked the 13th straight outing in which they managed two or more goals, and they will hope to build on that here.

Les Gones also have a strong run in away matches in the Europa League, carrying a 12-game unbeaten streak. They’ve never beaten Manchester United before.

This match, and the competition hold a lot of importance to these two teams’ seasons. Manchester United have attached their silverware hopes here, as well as their chances for Europe next season. Lyon may have a chance at Europe through their league standing, but this promises Champions League football too.

This is also Lyon’s only chance of winning silverware. We, therefore, expect to see a big effort from both teams here, and that could come in the shape of goals. Our prediction for Manchester United v Lyon is for over 2.5 goals.